The SD45 is a six-axle diesel-electric locomotive built by General Motors Electro-Motive Division between 1965–1971. It has an EMD 645E3 twenty-cylinder engine generating 3,600 hp (2,680 kW) on the same frame as the SD38, SD39, SD40, and SDP40. As of 2021, most SD45s have been retired, scrapped or rebuilt to SD40-2 standards.T
| Horsepower | Wheel Arrangement | Gearing | Weight | Tractive Effort | DRGW Class | Builder |
| 3600 | C-C | 62:15 | 389380 (5315-24) 389294 (5325-40) |
92890 92909 |
DE C-C 93 | EMD |
| Road # | EMD Builder # | Purchased | Retired | Notes |
| 5315 | 32689 | 1/1967 | . | Received large Rio Grande lettering as part of 10/1974 repaint [LIST] To OmniTRAX, Loveland, CO, 7/15/1994 [167] Leased to Nebraska Central #5315, 5/1997 [167] |
| 5316 | 32690 | 1/1967 | 12/1993 | To Morrison-Knudsen, 2/1994 [167] Rebuilt as SD40M-2 for CP Rail #5494, 3/31/1995 [167] |
| 5317 | 32691 | 1/1967 | . | To Progress Rail. To National Rail Equipment Corporation (NREX), 10/1995 [167] To Transglobal Rail Service #5317 [167] |
| 5318 | 32692 | 1/1967 | 12/1993 | To Morrison-Knudsen, 2/1994 [167] Rebuilt as SD40M-2 for CP Rail #5495, 4/13/1995 [167] |
| 5319 | 32693 | 1/1967 | 12/1993 | To Morrison-Knudsen, 2/1994 [167] Rebuilt as SD40-2 for SP #8678, 11/18/1994 [167] |
| 5320 | 32694 | 1/1967 | 9/10/1996 | To Helm Financial Corporation (HLCX) #6525, 3/26/1997 Rebuilt at VMV, Paducah, KY, 9/1997 |
| 5321 | 32695 | 1/1967 | 11/1994 | To Progress Rail to VMV, 5/1995 [167] Rebuilt as SD40-2 by Metro East Industries as KCS #634 [167] |
| 5322 | 32696 | 1/1967 | . | Received large Rio Grande lettering [LIST] |
| 5323 | 32697 | 1/1967 | . | National Rail Equipment Corporation 4/28/1997 [167] NRE, Mt. Vernon, IL, 11/1997 [167] |
| 5324 | 32698 | 2/1967 | . | . |
| 5325 | 33757 | 3/1968 | 6/14/1996 | To National Rail Equipment Corporation, 3/26/1997 [167] NRE, Mt. Vernon, IL, 11/1997 [167] |
| 5326 | 33758 | 3/1968 | 7/16/1997 | Received large Rio Grande lettering 2/1969 [LIST] |
| 5327 | 33759 | 3/1968 | 12/1993 | Received large Rio Grande lettering [LIST] To Morrison-Knudsen, 2/1994 Rebuilt as SD40-2, SP #8680, 11/28/1994 |
| 5328 | 33760 | 3/1968 | . | Received large Rio Grande lettering 2/1969 [LIST] To National Rail Equipment Corporation, 4/28/1997 [167] To NRE, Mt. Vernon, IL, 11/1997 |
| 5329 | 33761 | 4/1968 | . | Wrecked at Crater, CO, 12/25/1968, rebuilt by EMD Received large Rio Grande lettering 9.1969 [LIST] Damaged by fire, South Fontana, CA, 1/15/1995 [167] To Progress Rail, 5/1995 [167] To Metro East Industries, East St. Louis, IL [167] |
| 5330 | 33762 | 4/1968 | 12/1993 | To Morrison-Knudsen, 2/1994 [167] Rebuilt as SD40M-2, CP Rail #5496, 4/13/1995 [167] |
| 5331 | 33763 | 4/1968 | 5/7/1996 | Received large Rio Grande lettering 2/1969 [LIST] National Rail Equipment Corporation (NREX), 3/26/1997 [167] IMRL, 11/1997 [167] |
| 5332 | 33764 | 4/1968 | . | To OmniTRAX, 7/15/1994 [167] Leased to Nebraska Central #5332, 3/1997 [167] |
| 5333 | 33765 | 5/1968 | 12/1993 | Wrecked at Crater, CO, 12/25/1968, rebuilt by EMD Received large Rio Grande lettering 9/1969 [LIST] To Morrison-Knudsen, 2/1994 [167] Rebuilt as CP Rail SD40M-2 #5493, 3/31/1995 [167] |
| 5334 | 33766 | 4/1968 | 9/10/1996 | Received large Rio Grande lettering [LIST] To Helm Financial Corporation, HLCX #6522, 3/26/1997 [167] Rebuilt by Boise Locomotive Company, 11/15/1997 [167] |
| 5335 | 33767 | 5/1968 | 11/1992 | To OmniTRAX, Loveland, CO, 1995 [167] Empty shell may have been sold for preservation in vicinity of Denver, CO [167] |
| 5336 | 33768 | 4/1968 | 12/1993 | With 5337, first units to receive large Rio Grande lettering, 8/1968 [LIST] To Morrison-Knudsen, 2/1994 [167] Rebuilt as CP Rail SD40M-2 #5497, 4/17/1995 [167] |
| 5337 | 33931 | 3/1968 | 12/1993 | With 5336, first units to receive large Rio Grande lettering, 8/1968 [LIST] To Morrison-Knudsen, 2/1994 [167] Rebuilt as SP SD40-2 #8682, 12/2/1994 [167] |
| 5338 | 33932 | 3/1968 | 12/1993 | Received large Rio Grande lettering 2/1969 [LIST] To Morrison-Knudsen, 2/1994 [167] Rebuilt as SP SD40-2 #8684, 12/9/1994 [167] |
| 5339 | 33933 | 3/1968 | 9/10/1996 | To National Rail Equipment Corporation NREX, 7/1997 [167] |
| 5340 | 33934 | 3/1968 | 6/1/1996 | Received large Rio Grande lettering [LIST] To Helm Financial Corporation HLCX #6524, 3/26/1997 Rebuilt by Boise Locomotive Company, 11/5/1997 [167] |
